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THERMOstar
微孔板培养箱和轨道式振荡器
CLARIOstar Plus
面向研发应用的高灵活度多功能微孔板读板仪
CLARIOstar® Plus 是一款高灵活性的多功能微孔板读板仪，专为分析开发与复杂检测需求而设计。系统集成专利 LVF 光栅技术（线性可变滤光片）、滤光片与分光检测模块，在保证高度灵活性的同时，实现同类产品中领先的检测灵敏度。
结合新一代动态范围扩展技术（Enhanced Dynamic Range, EDR），CLARIOstar Plus 能够在宽动态范围内实现高精度检测，是方法开发与多样化分析应用的理想平台。
CLARIOstar Plus
CCLARIOstar® Plus 是一款面向复杂分析需求设计的多功能微孔板读板仪，集成 LVF 光栅、滤光片系统与超高速 UV/Vis 光谱检测模块，在灵活配置与检测性能之间实现高水平平衡。
通过引入扩展动态范围技术与全自动对焦功能，系统可自动完成增益与焦距优化，显著简化参数设定流程，提高实验重复性与数据可靠性。
结合大气控制单元（ACU）、温控孵育、多模式振荡、孔扫描及自动进样系统，CLARIOstar Plus 能够满足各类活细胞实验对环境控制与动态检测的严格要求，是开展细胞功能研究与复杂生物分析的理想平台。
此外，CLARIOstar Plus 搭载全新 Voyager 控制界面，在保证高度灵活性的同时优化操作流程，使方法建立与数据采集更加直观高效。
CLARIOstar Plus 仅用于科研用途。
特点
- 创新的LVF光栅技术，用于提高灵敏度
- 支持任意波长与带宽设置
- 在吸光度（AS）、荧光强度（FI）及发光（LUM）模式下进行光谱扫描
- 拥有无需人工干预的最大检测动态范围
- 整板快速自动对焦
- 基于活细胞的分析的专用功能
- 超快速数据采样（100次检测/秒）
- 配备 AlphaScreen® / AlphaLISA® 等技术的专用激光光源
服务于全球科研与工业机构：
CLARIOstar Plus
可选配件
酶标仪技术
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CLARIOstar Plus 的维护要求是什么？
BMG LABTECH 微孔板读数仪具有高度的稳固性和可靠性，无需对光学组件进行校准。建议的维护包括调整板载托架偏移、清洁光学组件、软件/固件更新以及常规性能检查。 -
维护费用和服务方案有哪些？
BMG LABTECH 提供灵活的维护方案，以确保长期性能。费用取决于所选择的方案。请通过服务合同表格与我们联系。 -
BMG LABTECH 是否为 CLARIOstar Plus 提供技术支持或培训？
是的，我们提供全面的技术支持和培训服务，帮助用户最大化仪器的性能。欢迎联系我们了解更多信息。 -
在哪里可以找到 CLARIOstar Plus 的更多信息或购买选项？
您可以在 CLARIOstar Plus 产品页面查看详细的产品信息、技术规格和可用配置。若需购买选项、报价或个性化建议，如需购买选项、报价或个性化推荐，请向我们的销售团队提交请求。 -
如何申请额外滤光片？
您可通过我们的滤光片申请表格来获取额外滤光片的报价。 我们将根据您的实验配置提供相应方案。 -
在哪里可以找到我的 CLARIOstar Plus 的使用手册？
每台仪器都附带用户手册。如果您遗失了手册，请使用我们的手册申请表获取副本。 -
在哪里可以找到 CLARIOstar Plus 的软件？
软件随仪器附带，可安装在任意数量的电脑上。它位于随手册附带的 USB 闪存盘（或旧型号的光盘）中。如果您遗失了 USB 或光盘，我们可以提供下载链接。请联系软件支持团队。 -
BMG LABTECH 为 CLARIOstar Plus 提供的软件是否兼容 Windows 11？
是的，该软件完全兼容 Windows 11。如需帮助确保正常使用，或在安装或兼容性方面有疑问，请联系软件支持团队。 -
CLARIOstar Plus 的购买成本是多少？
成本因所选配置而异。请联系我们以获取个性化报价。 -
是否有优化微孔板测量的教程？
是的，我们提供全面的 How-To Notes，解释常见检测参数、其对结果的影响以及实际优化技巧。您可以在 How-To Notes 页面找到这些资源。 -
典型的交货时间是多久？
设备交付时间将根据库存状态、具体配置方案及交付地区有所差异。
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Detection modes
Fluorescence intensity (incl. FRET)
Fluorescence polarization
AlphaScreen®/AlphaLISA®/AlphaPlex™
Luminescence (flash and glow) - incl. BRET
Time-resolved fluorescence
TR-FRET
UV/vis absorbance spectra
Measurement modes
Top and bottom reading
Endpoint and kinetic
Sequential multi-excitation
Sequential multi-emission
Spectral scanning (fluorescence, luminescence, absorbance)
Ratiometric measurements
Well scanning
Microplate formats
6- to 1536-well plates, user-definable
LVis Plate with 16 low volume microspots (2 μL)
Microplate carrier
Robot compatible
Light sources
High energy xenon flash lamp
Dedicated laser for AlphaScreen®/AlphaLISA®/AlphaPlex™
Detectors
Low-noise photomultiplier tube
Red-shifted photomultiplier tube
CCD spectrometer
Wavelength selection
Dual Linear Variable Filter (LVF) Monochromators™
Linear Variable Dichroic Mirror
Separates ex & em LVF Monochromators
Optical filters:
Ex and em slides hold 4 filters each
LVF Monochromators + optical filters
Use one for ex and the other for em
UV/Vis absorbance spectrometer:
Full spectra or 8 distinct wavelengths in < 1 sec/well
Spectral range
Filters
FI, FP, TRF: 240 - 740 nm or 240 - 900 nm (red-shifted PMT)
LUM: 240 - 740 nm
LVF Monochromators™
FI: 320 - 740 nm or 320 - 840 nm (red-shifted PMT)
LUM: 320 - 740 nm
Linear Variable Dichroic
340 - 740 nm or 340 - 760 nm (red-shifted PMT)
Spectrometer
ABS: 220 - 1000 nm; wavelength precision: ≤ 0.5 nm
Sensitivity
FI filters
(top)
< 0.15 pM (< 3 amol/well FITC, 384sv, 20 μL).
FI filters
(bottom)
< 1.0 pM (< 50 amol/well FITC, 384g, 50 μL).
FI monochromator
(top)
< 0.35 pM (< 7 amol/well FITC, 384sv, 20 μL).
FI monochromator
(bottom)
< 3.0 pM (< 150 amol/well FITC, 384g, 50 μL).
Dynamic Range: 8 decades in a single measurement.
FP
< 0.5 mP SD at 1 nM FITC (384sv, 20 μL).
HTRF®
(black and white microplates)
Reader Control Kit (Eu) after 18h (384sv, 20 μL).
Delta F > 880% (High Calibrator).
Delta F > 30% (Low Calibrator).
TRF
< 20 fM europium, 384, 80 μL (<1.6 amol/well).
LUM
< 0.4 pM (< 8 amol/well ATP, 384sv, 20 μL).
Dynamic range: 8 decades in a single measurement.
AlphaScreen® with laser.
< 5 pM (< 100 amol/well P-Tyr-100, 384sv, 20 μL).
ABS with spectrometer.
Selectable spectral resolution: 1, 2, 5, and 10 nm.
OD range: 0 to 4 OD; photometric resolution: 0.001 OD.
Accuracy: < 1% at 2 OD.
Precision: < 0.5% at 1 OD and < 0.8% at 2 OD.
Linearity: ≤ 0.8% at 2.0 OD.
Read times
Flying mode (1 flash)
8 s (96), 15 s (384), 28 s (1536)
10 flashes
19 s (96), 57 s (384), 3 min 4 s (1536)
Shaking
Linear, orbital, and double-orbital with user-definable time and speed
Incubation
+3 °C above ambient up to 45 °C or 65 °C
The upper heating plate of the incubation chamber operates at 0.5 °C more than the lower plate. This prevents condensation build-up on the lid or sealer
Software
Multi-user reader control (SMART Control and Voyager) and data analysis software (MARS). Voyager is compatible with CLARIOstar Plus readers from serial number 430-4001.
FDA 21 CFR Part 11 compliance available with SMART Control and MARS.
Integrated fluorophore library.
Dimensions
Width: 45 cm, depth: 51 cm, height: 40 cm; weight: 32 kg
Optical filters
Excitation and emission slides for 4 filters each
Optical path guides
Top and bottom: free-air optical light path guided by motor-driven mirrors and dichroics
Z'adjustment
Automatic focal height adjustment (0.1 mm resolution)
Reagent injection
Up to 2 built-in reagent injectors
Individual injection volumes for each well: 3 to 500 µL (optionally up to 2 mL)
Variable injection speed up to 420 µL/s
Reagent back flushing
Integrated barcode reader
Up to two integrated barcode readers
Power requirements
- 100 or 115 or 230 V, 50/60 Hz, auto ranging
Power consumption
- Normal operating conditions: 50 W
- Idle State: 20W
- Switched off: 0W
- max. 300 VA
Optional Accessories
LVis plate
Sample capacity: sixteen separate microdrop wells for 2 µL samples; one standard cuvette position for up to 1 mL samples
Quality Control Internal Standards (optional): four NIST traceable optical density filters (approximate values of 0.1, 0.3, 0.6 and 1.0 OD); one holmium oxide filter for wavelength accuracy
Dimensions: conforms to SBS standards for microplates
THERMOstar
Microplate incubator and shaker
Atmospheric control unit
Actively regulates O2 and CO2 - 0.1-20%
Stacker
Magazines for up to 50 plates - continuous loading feature. Only compatible with SMART Control.
Optical filters
Excitation and emission filters
Upgrades
The CLARIOstar Plus can include all or any combination of features listed below at purchase. Upgrading with additional features is possible at any time
Please contact your local representative for more details or a quote
*
LOD = 3 x SD (20 blanks) / slope (6 pt std curve)
AlphaScreen® P-Tyr-100 assay kit, PerkinElmer, #6760620C
Microplates: white for LUM, AlphaScreen®, TRF; black for FI, FP; clear for ABS
96 = 96-well microplates
384sv = 384-well small volume microplates
384g = 384-well glass bottom microplates
1536 = 1536-well microplates
The CLARIOstar Plus is for research use only.