Detection of bacterial endotoxins using the PYROSTAR™ ES-F/Plate LAL assay
Perform the PYROSTAR ES-F/Plate LAL test your way— BMG LABTECH readers support both turbidimetric and nephelometric evaluation for maximum flexibility.
NEPHELOstar® Plus 是全球首款基于激光技术的微孔板浊度分析仪,专为高通量复合物溶解度筛选而设计。
该系统通过检测前向散射光信号,定量分析液体样品中的不溶性颗粒,可用于浊度测量及多种相关应用,包括药物溶解度筛选、蛋白结合动力学研究、微生物生长监测以及工业过程控制(如石油加工)。

NEPHELOstar Plus 配备高强度激光二极管光源,是一款基于激光散射原理的微孔板浊度分析仪。与传统基于透射光密度(OD)的检测方法相比,该系统通过测量前向散射信号实现分析,灵敏度提升约 30 倍。
凭借高速检测性能、高灵敏度与良好的方法灵活性,NEPHELOstar Plus 可将激光散射浊度分析拓展至更广泛的微孔板应用场景。
NEPHELOstar Plus 仅用于科研用途。

Perform the PYROSTAR ES-F/Plate LAL test your way— BMG LABTECH readers support both turbidimetric and nephelometric evaluation for maximum flexibility.
Nephelometric turbidity units (NTUs) refer to the concentration of particles to describe the quality of water. Read how the NEPHELOstar® Plus microplate nephelometer determines NTUs in low sample volume.
Laser nephelometry was used for the rapid determination of the solubility of potential antimycotic drug compounds and for the measurement of fungal growth in the microplate format.
An alternative method to test Rheumatoid Factors by microplate nephelometry provides an inexpensive assay that can be used in medium- to high-throughput labs. Read more here!
Laser nephelometry is a reliable and sensitive technique to monitor microbial growth. Check out its good correlation with absorbance turbidity measurements in this AppNote!
Tired of performing solubility tests for your compound libraries? Nephelometry offers a rapid, reliable and low-cost method for kinetic solubility screenings in high-throughput!
Nephelometry (light scattering)
Endpoint and kinetic
Up to 384-well plates
Robot compatible
Self-monitoring laser diode
Wavelength 635±10 nm
Stability <0.2% deviation
Lifetime 20,000 hours
Output: 1 mW
Selectable beam width: 1.5 to 3.5 mm
Selectable intensity 0-100%
Scattering angle: detects up to 80° full cone angle
Side window photodiode detector
Photodiode
Wavelength 635±10 nm
Depending on particle size and liquid properties
Silica detection (particle size 0.5 to 10 µm) 800 nM
Dynamic Range: 5 decades
Maximum count rate (2,000,000 Relative Nephelometry Units (RNUs) per second)
Depend on assay conditions and liquid surface stability
Shortest times possible: 16 s (96), 47 s (384)
Linear, orbital, and double-orbital with user-definable time and speed
System to inject an atmosphere or to pull a vacuum into the reader
+4 °C above ambient up to 45 °C
The upper heating plate of the incubation chamber operates at 0.5 °C more than the lower plate. This prevents condensation build-up on the lid or sealer
Multi-user Reader Control and MARS Data Analysis Software included
FDA 21 CFR Part 11 compliant
Width: 44 cm, depth: 48 cm, height: 32 cm; weight: 25 kg
Up to 2 built-in reagent injectors
Injection at measurement position (6 to 384-well)
Individual injection volumes for each well (3 to 500 µL)
Variable injection speed up to 420 µL/s
Up to four injection events per well
Reagent back flushing
Microplate incubator and shaker
Actively regulates O2 and CO2 0.1-20%
Magazines for up to 50 plates - continuous loading feature
Please contact your local representative for upgrades including options such as detection modes, reagent injectors, etc